IMAGINE if you could isolate one of the most powerful regenerative components of your OWN blood and simply inject it into any area eg the face for anti ageing, scalp for hair thinning/loss or vagina for laxity, incontinence and other symptoms. IMAGINE if this isolate contained 100 times the circulating stem cells (CD34+) of whole blood or even 10-20 times that of bone marrow! Well IMAGINE NO MORE…..for one of our most exciting treatment launches is here! iPRF (Injectable Platelet Rich Fibrin) is the next generation in anti-ageing and surpasses the better known PRP, by a huge distance. Yet again, Perfect Skin Solutions is at the very forefront of the aesthetic industry. Our medical director, Dr Dev Patel, has trained with the global regenerative expert and plastic surgeon, Mr Ghanem, who introduced iPRF to the UK and ours is one of the first clinics to roll this out beyond his practice.

Injectable platelet rich fibrin or (iPRF) uses the patient’s own blood plasma which is enriched with:
  • platelets (source of healing proteins and growth factors)
  • fibrin (the wound healing and regeneration matrix)
  • stem cells (the conductors of our body’s own healing and regenerative orchestra of healing and regeneration molecules).
Patented technology invented by Dr Joseph Choukroun in 2016, allows us to isolate various fractions from whole blood taken from the patient. This can then be injected via a very fine needle (technique used in mesotherapy) into the area(s) of concern, to activate healing and regeneration. Although this is from the patient’s own body, no area would naturally get exposure to such a potent concentration of biostimulating and regenerative cells. However, the process that is triggered is totally innate and natural.
iPRF intensifies the functioning and reproduction of cells, thus having a gentle, gradual yet long lasting and accumulative effect. As a result new fibroblasts, collagen and elastin tissues are formed, skin elasticity and complexion is improved, and the pigmentation is reduced. Its uses are not limited to skin rejuvenation.
Potential uses:
  • Skin rejuvenation
  • Scarring
  • Stretch marks
  • Hair loss/thinning
  • Vaginal rejuvenation
  • Acne
  • Procedures – enhancing results and reducing downtime
  • Joint and soft tissue disorders eg tennis elbow, plantar fasciitis


Treatment Summary

  • Procedure Time 30 mins
  • Full Recovery Immediate
  • Duration of Results Dependant on medical/lifestyle factors
  • Back To Work Time Immediate
  • Sensitivity Period 24 hours
  • Anaesthetic None Required (except hair iPRF)
  • Risks & Complications Bruising


For a singular treatment in one area – £595

For a course of 3 in one area – £1495

Combination treatments are available and can be discussed on consultation as will be subject to further discount.


  • No bath/shower for 4 hrs (thereafter, luke warm water only for 24 hrs)


What is the difference between iPRF & PRP?

Both PRP (platelet rich plasma), and PRF (platelet rich fibrin) are platelet based growth factor treatments that are extracted using centrifuge. PRF is different from PRP in that there is no anticoagulant added during the spin, the avoidance of clotting is physiological and is achieved through negative charge of the collecting tube to mimic the conditions within our own blood vessels (their lining is negatively charged) that prevent fibrin from creating a clot within them, thus, obtaining a platelet rich injectable fibrin. Once PRF is injected in the tissue it transforms from liquid into a gel, which not only lead to filling of voids in folds and wrinkles but also provide a powerful regenerative matrix that releases platelets’ growth factors in a physiological controlled slow manner that enhances tissue regeneration is a better way than PRP.
In addition, the enrichment of platelets in these two products is not the same. In PRP, the platelets are enriched two to four times above the physiological concentrations available in blood and there are very few circulating blood stem cells. In contrast, PRF contains all the platelets with no elimination of the powerful regenerative matrix (fibrin) in addition to another very rich source of growth factors and tissue regeneration: the circulating blood stem cells.

Is there evidence to support what iPRF does?

YES. Injury to any human tissue (ageing is also injury) will immediately result in platelet growth factors in a fibrin scaffold are the first response to injury observed in all human tissue. Accelerated healing, new blood vessels and proliferation of cells producing collagen (fibroblasts) have been well demonstrated in biomedical research investigating the basic functions of this regenerative products. Even its predecessor – PRP – has been shown to significantly accelerate healing in tissues and is widely used in the aesthetic field too.

Why is fibrin important?

Dr Choukroun explains that Fibrin functions as a matrix that traps the platelets and controls their release of growth factors “very slowly and continuously over a time period of more than one week”. Growth factors release rate into the target tissue is important for tissue receptors to respond over a prolonged period of time following treatment.  “It’s not the amount of growth factors that’s the most important, but it is released into the site. To treat severe infection, antibiotics can be injected drop by drop in an IV perfusion, ensuring that a stable concentration is maintained. This is the same in PRF biology—to obtain the most important function a stable concentration must be maintained. The best is a drop-by-drop infusion”

How does it help with hair loss?

iPRF is a natural way to help male and female hair thinning.  iPRF can enhance the growth of hair follicles by stimulating the stem cells and other cells in the microenvironment of the hair follicle. These special platelet cells promote healing and accelerate the rate and degree of tissue regeneration, resulting in new hair growth and thickening of existing hair.