face/body Treatment
EndoDefine
EndoDefine is a minimally invasive laser treatment designed to tighten skin, improve facial definition and contour targeted areas of the face and body. It can be considered for patients looking to address mild to moderate skin laxity and small areas of unwanted fat without traditional surgery.
What is EndoDefine?
EndoDefine is a minimally invasive laser treatment that gives ultimate skin tightening and rejuvenation. This technology addresses skin ageing, excess fat tissue and loss of facial definition. Using laser energy, EndoDefine targets and reshapes the underlying tissues to give a more toned, sculpted, youthful look. Whether you have sagging skin, small fat deposits or loss of facial definition EndoDefine is the solution to get your youthful face back.
What does EndoDefine Do?
Using optical fibre and precise energy delivery, the EndoDefine diode laser targets small fatty deposits and helps to tighten loose skin. This minimally invasive laser procedure is safe and approved to reduce excess fat and assist with skin tightening.
How Long Will It Take To See Results?
Slight results will be visible immediately and will improve post-treatment. You should expect to see a large difference within a few weeks.
Our EndoDefine Treatment with CellDerma GF5
We always combine EndoDefine with CellDerma GF5 topical growth factor treatment, which is provided complementary. CellDerma GF5 contains a cocktail of bioidentical growth factors and other regenerative and hydrating ingredients, to significantly promote both healing after your EndoDefine and overall results. If so desired, this can be continued longterm.
Treatment areas: skin tightening
- Lower face (jowl) and neck ‘sagging’
- Eye area skin laxity
- Scarring
- Upper arms
- Thighs
- Knees
EndoDefine is suitable for mild to moderate skin laxity.
After local anaesthetic, EndoDefine uses laser technology to target specific areas, and stimulates multiple responses:
- Mechanical contraction for immediate skin firming and tightening
- Improvement of skin ‘architecture’ through natural production of structural proteins like collagen and elastin
- Skin surface rejuvenation due to the kickstarted healing process
- Fat reduction by targeting fat cells and contracting the Fibroseptal network
The treatment takes about an hour. Due to EndoDefine’s minimally invasive nature the downtime is very short. Patients will have slightly pink skin and mild swelling for 24-48 hours.
In most cases, only one treatment is needed but this varies from person to person. You will be advised on the number of treatments required for optimal results during your consultation.
EndoDefine is designed to give long-term skin tightening and subdermal rejuvenation, for laser-assisted facelift procedures. The technology targets skin laxity, promotes collagen production and reduces fat deposits to redefine the face, similar to Endolift but with its own unique approach and technology. Sun exposure is a major contributor to facial ageing and EndoDefine addresses this.
For patients exploring other skin tightening and facial contouring options, treatments such as FaceTite or Morpheus8 Skin Tightening may also be considered following consultation.
Why choose Perfect Skin Solutions for your EndoDefine?
EndoDefine Diode Laser Treatment
At Perfect Skin Solutions, EndoDefine treatment is performed by Dr Dev Patel following a detailed consultation and assessment of your individual concerns, anatomy and treatment goals.
Dr Patel is experienced in advanced aesthetic treatments and is a speaker for EndoDefine. Treatment is carefully planned for each patient, with consideration given to the areas being treated, skin laxity and facial or body contours to determine whether EndoDefine is an appropriate option.
Safety and Effectiveness
EndoDefine uses controlled laser energy delivered beneath the skin, with an integrated HD thermal imaging system that allows the doctor to monitor tissue temperature and treatment response in real time. This helps support precise energy delivery throughout the procedure.
As with any aesthetic procedure, EndoDefine carries potential risks and side effects. Your suitability will therefore be assessed during consultation with Dr Dev Patel, who will discuss the expected benefits, potential risks, recovery and whether EndoDefine is appropriate for your individual concerns.
How EndoDefine Works
EndoDefine works by delivering controlled laser energy into the skin, stimulating collagen production and firming of skin structures. The treatment uses a microfibre tip to gently sweep the area underneath the surface, melts small fat deposits in the face. This stimulates natural collagen production and reorganisation of existing tissue fibres, both deep and superficial layers of the skin. EndoDefine gives optimal skin tightening and rejuvenation, addresses facial oval sagging, neck laxity and excess fat accumulation. No surgery needed.
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At a glance
Full recovery
Downtime - 3 -7 days. Full recovery - Variable.
Back to work time
24-48 hours
Sensitivity period
Mild redness and swelling, bruising
Duration of result
Bruising, spot burn, discomfort




