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face/body/skin Treatment


With 41 years of scientific research and development, 36 years of medical application, 1.8 million uses and no adverse or allergic reactions, Polynucleotides are the gold standard in true skin regeneration. Utilising filtered, ultra purified and sterilised natural DNA fractions, this injectable serum offers some serious benefits and incredible, visible results.

With over 90 clinical trials and a proven track record in tissue and cartilage regenerative medicine, the evidence for the power of Polynucleotides is undisputed in both the medical and aesthetic fields. Once filtered and ultra-purified, natural DNA fractions initiate your body’s natural fibroblast production, resulting in increased collagen (47% in 23 days) and a thicker, healthier epidermis (52% in 23 days). Thanks to polynucleotides’ antioxidant properties, inflammation is reduced and youthful volume and hydration is restored. The list of applications seem endless, but key uses include;

  • Holistic skin revitalisation to combat general signs of ageing
  • Preparation and recovery pre/post procedures and surgeries (medical & aesthetic)
  • Acne
  • Atrophic scarring
  • Rosacea
  • Elastosis
  • Alopecia/hair loss
  • Hyperpigmentation
  • Stretch marks
  • Deep lines & wrinkles
  • Rehydration for dull skin at any age
Perfect Skin Solutions

Why choose Perfect Skin Solutions for your Polynucleotides?

Dr Dev Patel is a global speaker on the topic of Regenerative Medicine and is recognised as one of the early adopters of cutting-edge treatments such as Exosomes, he was thus privileged to be one of the first UK doctors to incorporate Polynucleotides into his treatment protocols. Always at the forefront of the very best the medical aesthetics industries have to offer, Dr Patel has researched and studied extensively to source the highest concentration of polynucleotides available on the market. Having treated numerous patients, we are seeing exciting results. Dr Patel has personally mentored and trained our highly qualified Aesthetic Nurses, who will carry out many of our polynucleotide treatments, though appointments with Dr Patel can be made on request.

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At a glance At a glance

At a glance

Treatment time

15 - 30 mins


Dependent on area

Full recovery

0 to 36 hours

Back to work time


Sensitivity period


Duration of result


Risks & complications

Bruising, temporary swelling


Nurse prices

One treatment (2ml syringe)


Course of three treatments


Saves £135

Course of five treatments


Saves £380

Doctor prices

One treatment (2ml syringe)


Course of three treatments


Saves £165

Course of five treatments


Saves £400


You may have tiny blebs just visible, which is where the product has been left on your skin. This will dissipate over a few hours but can take longer in some patients.

  • Avoid any other facial treatments for 72 hours
  • Avoid touching or washing your face for 4 hours
  • Avoid make-up for 12 hours
Face Treatment AftercareFace Treatment Aftercare



This is quite possibly the most asked question! And it’s a good one! The DNA used originates from salmon! Remarkably, salmon DNA is incredibly similar to ours. But rest assured; we are referring only to FRACTIONS of DNA. After the highly specialised clinical filtration and ultra-purification process, there is no ‘matter’ remaining. Even those with allergies to fish are safe to use polynucleotides, with clinical trials reporting NO allergic reactions to date. We should also note that the salmon are not killed to obtain their DNA.

Polynucleotides are suitable at any age, at any time of year.

Whilst there is a benefit to having even one syringe of polynucleotides, we recommend a course of at least 3, each spaced 3 weeks apart.

Polynucleotides can also be incorporated into skin booster treatments such as Profhilo and Sunekos, and many more of the treatments we offer. Your practitioner will be able to guide you through how and when to introduce a protocol.

The first signs of improvement often begin around 7-10 days after your first treatment, with the full effects visible at around 3-4 weeks. This is when we recommend your second, and subsequent treatments to take place. By doing so, we maintain continued, active stimulation of fibroblast production, maximising short and long-term results.

Polynucleotides differ from other, hyaluronic-based skin boosters and dermal fillers. Rather than giving skin a surge in collagen and elastin, or ‘plumping’ the skin with carefully placed temporary products, polynucleotides are catalysts in the regeneration of fibroblasts – the main cells within the skin’s structure. The product itself is absorbed by the body fairly rapidly, having activated new cell production. Of course, we continue to age, but the clock has quite literally been turned back in your treated areas.

Polynucleotides are filtered and ultra-purified natural DNA fractions that initiate your body’s natural fibroblast production, resulting in increased collagen (47% in 23 days) and a thicker, healthier epidermis (52% in 23 days).