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exosomes

face/body Treatment

Exosomes

This breakthrough treatment is now available at our clinic! Exosome therapy is one of the most exciting treatments in the medical and aesthetic world today. Dr. Dev Patel launched Exosome therapy at Perfect Skin Solutions in 2020 and this is as cutting-edge as it gets. Exosomes are the signalling messengers from stem cells and have a whole host of potential benefits and applications, especially for skin health. In fact, all aspects of skin health improve with exosome therapy. We only offer Exosomes from 2 sources, plant (EXO|E) and salmon (E-50). Human-sourced exosomes do NOT comply with EU regulations for cosmetic products and cannot be used, even topically. Specific Skin Concerns Addressed Exosomes are versatile and can be tailored to address a variety of specific skin concerns, including: Fine lines and wrinkles: Exosome therapy enhances the skin's ability to repair and rejuvenate itself, softening fine lines wrinkles over time. Sagging skin: By stimulating collagen and elastin, exosome treatments restore the firmness and elasticity of the skin, combating signs of ageing. Uneven skin texture: Exosomes help smooth out the skin's surface, reducing the roughness often associated with ageing and sun damage. Hair follicles: Exosome therapy can also be used to promote the health of hair follicles, aiding in hair growth treatments.

Exosome treatments are an innovative approach to skincare that promotes youthfulness by stimulating collagen production and enhancing cellular renewal. We only use brands of exosomes fully regulated for cosmetic use (CE marked) that also have a significant weight of clinical evidence to support its efficacy, even with topical use.

Applications include:

  • Pigmentation
  • Skin laxity
  • Dull skin
  • Lines & wrinkles
  • Scarring
  • Acne
  • Dermatitis e.g. eczema
  • Rosacea
  • Other inflammatory conditions eg lichen simplex, psoriasis
  • Hair thinning/loss (male and female)

(Please note: there may only be anecdotal or other limited evidence for exosome therapy in some of the above conditions. However, research in a multitude of conditions has shown very promising results).

THE EXO|E COMPLEX SYSTEM

A complete set of active plant based secretory factors and the latest bio-based, patented technology for modern skincare. Patients appreciate less downtime and enhanced aesthetic results. The EXO|E COMPLEX SYSTEM can be used to support treatments such as Morpheus 8, laser procedures and even injectables; reducing inflammation and downtime whilst enhancing results, or can be used as a stand alone treatment with or without micro-needling.

E-50 EXOSOMES

E50 Exosomes use a proprietary process, known as ENTR® Technology, to collect exosomes from the fibroblast cells of salmon testes and then cultivate these exosomes in dermis stem cell media. This method uses ultrasound and enables the creation of exosomes which are CUSTOMISED for skin rejuvenation. Both the cell host and the cell media which are utilised in the creation of E50 Exosomes are fully salmon derived.

By utilising salmon cells, this ensures that E50 Exosomes have low levels of free radicals and impurities. Using ENTR® Technology, this enables to limit the doubling time of the harvested exosomes. This quicker process allows for a final product which is HOMOGENOUS and PURE with up to 10,000 fold more exosomes per unit than other exosomes.

What are Exosomes?

Exosomes are tiny extracellular vesicles that are secreted by stem cells and other cell types. They are approximately 30-150 nanometers in size and contain a complex mixture of bioactive molecules, including growth factors, proteins, and genetic material. Exosomes play a vital role in intercellular communication, facilitating the exchange of information between cells and influencing various cellular processes, including skin repair and regeneration.

Benefits of Exosomes for Skin Rejuvenation

Exosomes offer a multitude of benefits for skin rejuvenation, including:

  • Improved skin texture and elasticity
  • Enhanced collagen and elastin production
  • Reduced fine lines and wrinkles
  • Improved skin health and hydration
  • Addressing specific skin concerns, such as acne scars and hyperpigmentation
  • Promoting hair growth and improving hair follicle health

By harnessing the power of exosomes, you can achieve a more youthful and radiant complexion, while also addressing specific skin concerns and promoting overall skin health.

Perfect Skin Solutions

Why choose Perfect Skin Solutions for your Exosomes?

TargetCool: Precision Cooling for Comfort

TargetCool is a portable medical device that uses advanced cooling technology to deliver exosome treatments with precision and comfort. It provides a pain-free and highly effective way to enhance skin and tissue health.

How It Works:

TargetCool uses CO₂ Jet Propulsion Therapy, a needle-free method powered by Carboxytherapy. This involves introducing CO₂ gas to the skin, which stimulates oxygenation and boosts blood flow. This improves the absorption of exosomes and other nutrients. During treatment, a gentle cooling sensation (about 2°C) enhances comfort and promotes better results

Optional Microneedling:

For enhanced effectiveness, microneedling can be added. This creates microchannels in the skin, allowing deeper penetration of exosomes and nutrients. Microneedling is optional—TargetCool works effectively on its own for a non-invasive experience or can be combined for more noticeable results.

Dr Dev Patel is recognised as one of the pioneers of exosome therapy in the UK and abroad, having first used this in 2020. He has been interviewed by and featured in publications such as the Aesthetic Medicine Journal, The Evening Standard and Get the Gloss, talking about the subject. British Vogue recently focused an article around his comments on stem cells in skincare and his reputation within the sphere of regenerative medicine is far-reaching. Indeed, Dr Dev Patel is the Founder of the award-winning skincare brand CellDerma which makes the GF5 bio-regenerative growth factor serum, a leader in topical regenerative therapy.

Dr Patel has patients travelling from as far as the USA and Middle East for exosome therapy. He was invited to speak on Exosomes at the global FACE conference in London in 2022 to an audience of international medical practitioners. Dr Patel has personally trained and mentored our entire clinical team on the use of exosomes so you will be in good hands with one of our therapists or nurses. However, if you specifically wish to see Dr Patel, this may be possible to arrange after consideration of your case.

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At a glance At a glance

At a glance


Treatment time

15 - 30 mins

Anaesthetic

Topical

Full recovery

12 hours (in most cases)

Back to work time

Immediate

Sensitivity period

1 hour

Duration of result

N/A

Risks & complications

Bruising, temporary swelling

Prices

If you require a medical consultation with our doctor before treatment, this is charged at £120.

Face & Neck (or other area) or Scalp

from £395

1 treatment with a Therapist

£395

Course of 3 treatments with a Therapist

£1050

Saves £135

Course of 5 treatments with a Therapist

£1580

Saves £395

1 treatment with a Doctor

£495

Course of 3 treatments with a Doctor

£1325

Saves £160

Course of 5 treatments with a Doctor

£1980

Saves £495

Visia Facial Scan – £25

LifeViz Facial Scan – £50

LifeViz Body Scan – £50

 

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Aftercare


Exosome Treatment Process

The exosome treatment process typically involves applying exosomes to the treatment site via microneedling.  This allows the exosomes to penetrate deep into the skin layers, where they can interact with skin cells to promote healing and regeneration. Unlike dermal fillers or cosmetic surgery, exosome therapy is non-invasive and requires minimal downtime, making it an ideal option for those looking for natural skin rejuvenation.

You may have tiny blebs just visible, which is where the product has been left on your skin. This will dissipate over a few hours but can take longer in some patients.

  • Avoid any other facial treatments for 72 hours
  • Avoid touching or washing your face for 4 hours
  • Avoid make-up for 12 hours
Face Treatment AftercareFace Treatment Aftercare
Before & After

Before & After

Exosomes

FAQ

Exosomes are small vesicles that are naturally produced by cells and contain various bio molecules such as proteins, lipids and nucleic acids. They play a role in cell to cell communication and have been found to be powerful in stimulating skin rejuvenation, hair growth and reducing inflammation in the skin.

Anyone who wants to improve the health and quality of their skin. It can be used for age-related issues, scarring and even eczema. Please note, many of these indications may not be listed under the approved use list for exosomes. These are regulated for cosmetic use and therefore must be seen as a product to help with skin rejuvenation. Treatments are often used ‘off-label’ in the world of medicine and some applications of exosomes may be offered under this premise, based on anecdotal evidence. This treatment is excellent as a combination protocol, alongside collagen-stimulating treatments like Morpheus8 or Fractora. Even one session with such treatments can deliver more powerful results. You can continue with topical growth factor treatment (CellDerma GF5) at home.

When you visit us for a consultation, we will look at your medical history and concerns and help you choose the right therapies for the best possible outcome.

Depending on your individual circumstances, Exosomes can help stimulate skin rejuvenation, promote new hair growth and reduce skin inflammation. They can also work really well combined with other treatments. A consultation can help us bespoke a treatment plan made just for you.

Exosomes are approved for topical use only. Your clinician may offer you micro-needling alongside topical exosome application to enhance the penetration of the product. However, topical use alone has been shown to be clinically effective.

YES. Your body makes and uses exosomes all the time and knows what to do with them. No long-term negative side effects have been reported with this treatment. Furthermore, our preferred products – Exo|E and E-50 – utilises purely plant or salmon-based exosomes which have been shown to have a bio-mimetic effect in humans (i.e. work like our own exosomes). Human-sourced exosomes do NOT comply with EU regulations for cosmetic products and cannot be used, even topically. Our chosen brands have had significant investment in Research and Development with a solid foundation of clinical evidence with regards to safety and efficacy.

Ideally 3-5 treatments, but this does depend on your individual circumstances, treatment goals and expectations. If used in combination with another treatment, then even one session can be very useful. Our consultation process will allow you to get a better idea of what may be best for you.

On average, most patients start to see signs of improvement after their 2nd or 3rd session but often earlier.

Exosomes offer a multitude of benefits for skin rejuvenation, including:

  • Improved skin texture and elasticity
  • Enhanced collagen and elastin production
  • Reduced fine lines and wrinkles
  • Improved skin health and hydration
  • Addressing specific skin concerns, such as acne scars and hyperpigmentation
  • Promoting hair growth and improving hair follicle health

By harnessing the power of exosomes, you can achieve a more youthful and radiant complexion, while also addressing specific skin concerns and promoting overall skin health.

Exosomes work by facilitating intercellular communication and influencing various cellular processes, including skin repair and regeneration. They contain a wealth of bioactive molecules, including growth factors, proteins, and genetic material, which are released into the skin and stimulate the production of collagen and elastin. This leads to improved skin texture and elasticity, reduced fine lines and wrinkles, and enhanced skin health and hydration.

Exosome treatment methods vary depending on the specific skin concern and individual needs. Common methods include:

  • Topical application: Exosomes are applied topically to the skin, where they penetrate deep into the skin and stimulate collagen and elastin production.
  • Microneedling: Exosomes are combined with microneedling, a minimally invasive treatment that creates micro-channels in the skin, allowing for deeper penetration and enhanced absorption.
  • Electroporation: Exosomes are combined with electroporation, a non-invasive treatment that uses electrical pulses to enhance absorption and penetration.
  • Injection: Exosomes are injected into the skin, where they stimulate collagen and elastin production and address specific skin concerns.

Each of these methods offers unique benefits and can be tailored to address your specific skin concerns, ensuring optimal results for skin rejuvenation and overall skin health.

Exosome therapy is an advanced skin treatment that uses exosomes derived from mesenchymal stem cells. These exosomes contain a rich concentration of proteins, lipids, nucleic acids, and growth factors, which promote tissue repair and stimulate cellular communication. When applied to the skin, exosomes work to rejuvenate skin cells by boosting the production of collagen and elastin, which are essential for maintaining skin elasticity and a youthful appearance.

Exosome skin therapy offers several benefits that make it a preferred choice for many seeking facial rejuvenation and skin treatment. Some of the most notable benefits include:

  • Improved skin tone: Exosome treatments help in achieving a more even skin tone by targeting uneven skin texture and pigmentation issues.
  • Reduction in fine lines and wrinkles: By stimulating collagen production, exosomes minimize the appearance of fine lines and deeper wrinkles, promoting a smoother, firmer complexion.
  • Facial rejuvenation: The regenerative properties of exosomes contribute to improving the skin’s texture and structure, helping combat sagging skin and improving overall skin’s appearance.
  • Skin hydration: Exosome treatments are known for enhancing the skin’s moisture retention, leading to healthier and more hydrated skin’s surface.
  • Acne scars: Exosome therapy is effective in reducing the visibility of acne scars by promoting tissue repair and restoring the skin’s natural healing processes.
  • Sensitive skin: The anti-inflammatory properties of exosomes help soothe sensitive skin, reducing skin inflammation and mild redness.

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